不仅仅是一个“水槽”：内体掌控信号转导。

Not just a sink: endosomes in control of signal transduction.

作者信息

Miaczynska Marta, Pelkmans Lucas, Zerial Marino

机构信息

Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany.

出版信息

Curr Opin Cell Biol. 2004 Aug;16(4):400-6. doi: 10.1016/j.ceb.2004.06.005.

DOI:10.1016/j.ceb.2004.06.005

PMID:15261672

Abstract

Recent studies indicate that endocytic organelles can play a more active role in signal propagation and amplification than was recognised before. By deciphering the interplay between endocytosis and signalling, we will be able to gain a more sophisticated level of understanding of signal transduction mechanisms.

摘要

最近的研究表明，内吞细胞器在信号传播和放大过程中所起的作用可能比以往认为的更为积极。通过解读内吞作用与信号传导之间的相互作用，我们将能够对信号转导机制有更深入的理解。