一项使用电流感觉阈值对腕管综合征中神经纤维受累情况进行的相关电生理研究。
A correlative electrophysiologic study of nerve fiber involvement in carpal tunnel syndrome using current perception thresholds.
作者信息
Nishimura Akiyo, Ogura Taku, Hase Hitoshi, Makinodan Atsushi, Hojo Tatsuya, Katsumi Yasukazu, Yagi Katsumi, Mikami Yasuo, Kubo Toshikazu
机构信息
Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.
出版信息
Clin Neurophysiol. 2004 Aug;115(8):1921-4. doi: 10.1016/j.clinph.2004.03.022.
OBJECTIVE
To relate clinical severity of idiopathic carpal tunnel syndrome (CTS) to current perception threshold (CPT).
METHODS
Subjects were 51 patients with CTS (involving 51 hands), and 50 healthy control subjects (50 hands). Involved hands were grouped into three clinical grades (mild, moderate, severe). Using a neurometer (Neurotron, Baltimore, MD), we investigated the relationship between clinical grade and CPT abnormalities.
RESULTS
In the mild CTS group, most hands showed CPT abnormalities only at 2000 Hz stimulation. The moderate group included a higher percentage of hands showing abnormalities at both 2000 and 250 Hz stimulation increased. The severe group included the highest percentage of hands with abnormal values at all frequencies tested.
CONCLUSIONS
CPT showed abnormalities appear progressively from 'higher to lower' frequency stimulations relative to the increasing severity of CTS.
SIGNIFICANCE
Sensory nerve fiber dysfunction apparently begins in larger fibers, extending stepwise to smaller fibers as the clinical grade of CTS progresses.
目的
将特发性腕管综合征（CTS）的临床严重程度与当前感觉阈值（CPT）相关联。
方法
研究对象为51例CTS患者（涉及51只手）和50名健康对照者（50只手）。患手分为三个临床等级（轻度、中度、重度）。使用神经测试仪（Neurotron，巴尔的摩，马里兰州），我们研究了临床等级与CPT异常之间的关系。
结果
在轻度CTS组中，大多数患手仅在2000Hz刺激时显示CPT异常。中度组中，在2000Hz和250Hz刺激时均显示异常的患手百分比更高。重度组中，在所有测试频率下数值异常的患手百分比最高。
结论
相对于CTS严重程度的增加，CPT异常从“高频到低频”刺激逐渐出现。
意义
感觉神经纤维功能障碍显然始于较大的纤维，并随着CTS临床等级的进展逐步扩展到较小的纤维。
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