Montgomery Erwin B
Department of Neurology, National Primate Research Center, University of Wisconsin-Madison, Wisconsin 53792, USA.
Neurosurg Focus. 2004 Jul 15;17(1):E1. doi: 10.3171/foc.2004.17.1.1.
Deep brain stimulation (DBS) has a record of safety and efficacy for an expanding range of indications. Recently,the Food and Drug Administration provided approval through a Humanitarian Device Exemption for DBS of the globus pallidus internus and subthalamic nucleus for the treatment of dystonia. There is increasing clinical experience demonstrating that DBS is also effective for other hyperkinetic disorders such as chorea from a variety of causes. The selection criteria, intraoperative targeting, and the postoperative management of DBS for hyperkinetic disorders are discussed.
对于越来越多的适应症，脑深部电刺激术（DBS）有着安全有效的记录。最近，美国食品药品监督管理局通过人道主义器械豁免批准了苍白球内侧部和丘脑底核的DBS用于治疗肌张力障碍。越来越多的临床经验表明，DBS对其他多种原因引起的运动亢进性疾病如舞蹈症也有效。本文讨论了运动亢进性疾病DBS的选择标准、术中靶点定位及术后管理。
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