深部脑刺激治疗偏侧舞蹈症：病例系列和文献复习。
Deep Brain Stimulation for the Treatment of Hemichorea: Case Series and Literature Review.
机构信息
Department of Neurosurgery, University of Kansas Medical Center, US.
Department of Neurological Surgery, Oregon Health & Science University, US.
出版信息
Tremor Other Hyperkinet Mov (N Y). 2023 Jun 12;13:21. doi: 10.5334/tohm.765. eCollection 2023.
BACKGROUND
Hemichorea (HC) and its severe form hemiballismus (HB) are rare movement disorders which can be medically refractory to treatments and may need surgical intervention.
CASE REPORT
We report 3 patients with HC-HB who had meaningful clinical improvement with unilateral deep brain stimulation (DBS) of the globus pallidus interna (GPi). We identified 8 prior cases of HC-HB treated with GPi-DBS, and a majority of these patients experienced significant improvement in their symptoms.
DISCUSSION
GPi-DBS can be considered in medically refractory HC-HB in carefully selected patients. However, data is limited to small case series and further studies are needed.
背景
偏侧舞蹈症（HC）及其严重形式——偏侧投掷症（HB）是罕见的运动障碍，可能对治疗有抗药性，需要手术干预。
病例报告
我们报告了 3 例 HC-HB 患者，他们接受单侧苍白球内侧部（GPi）脑深部电刺激（DBS）治疗后，临床症状有明显改善。我们发现了 8 例 HC-HB 接受 GPi-DBS 治疗的病例，这些患者的症状都有显著改善。
讨论
对于经过慎重选择的药物难治性 HC-HB 患者，可考虑 GPi-DBS 治疗。然而，目前数据仅限于小样本病例系列研究，还需要进一步研究。
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