Scarzella L, Bono G, Bergamasco B
Department of Neurology, University of Turin, Italy.
Int J Clin Pharmacol Res. 1992;12(1):37-46.
A double-blind, placebo-controlled, randomized study is described of an assessment of the efficacy and relative safety of the ergot alkaloid, dihydroergocryptine, on 52 patients with mild organic brain syndrome over a period of three months using a series of neurophysiological tests. The results indicated that short-term treatment with the alkaloid improved memory impairment. The side-effects were mild and transient in both the dihydroergocryptine and placebo groups and there were no alterations in blood chemistry.
本文描述了一项双盲、安慰剂对照、随机研究，该研究使用一系列神经生理学测试，对52例轻度器质性脑综合征患者进行为期三个月的麦角生物碱二氢麦角隐亭疗效及相对安全性评估。结果表明，该生物碱的短期治疗改善了记忆障碍。二氢麦角隐亭组和安慰剂组的副作用均轻微且短暂，血液化学指标无变化。
