Debesset S, Hayden C J, Dalton C, Eijkel J C T, Manz A
Department of Chemistry, Imperial College London, London SW7 2AY, UK.
Lab Chip. 2004 Aug;4(4):396-400. doi: 10.1039/b314123c. Epub 2004 Mar 25.
Flow rates of up to 50 microm s(-1) have been successfully achieved in a closed-loop channel using an AC electroosmotic pump. The AC electroosmotic pump is made of an interdigitated array of unequal width electrodes located at the bottom of a channel, with an AC voltage applied between the small and the large electrodes. The flow rate was found to increase linearly with the applied voltage and to decrease linearly with the applied frequency. The pump is expected to be suitable for circular chromatography for the following reasons: the driving forces are distributed over the channel length and the pumping direction is set by the direction of the interdigitated electrodes. Pumping in a closed-loop channel can be achieved by arranging the electrode pattern in a circle. In addition the inherent working principle of AC electroosmotic pumping enables the independent optimisation of the channel height or the flow velocity.
使用交流电渗泵在闭环通道中已成功实现高达50微米每秒的流速。交流电渗泵由位于通道底部的不等宽电极的叉指阵列构成,在小电极和大电极之间施加交流电压。发现流速随施加电压线性增加,随施加频率线性降低。该泵预计适用于循环色谱,原因如下:驱动力分布在通道长度上,且泵送方向由叉指电极的方向设定。通过将电极图案排列成圆形可在闭环通道中实现泵送。此外,交流电渗泵送的固有工作原理使得能够独立优化通道高度或流速。