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垂直毛细阵列泵的协同抽吸作用控制微流控传感器芯片的流动剖面。

Cooperative suction by vertical capillary array pump for controlling flow profiles of microfluidic sensor chips.

机构信息

NTT Microsystem Integration Laboratories, Nippon Telegraph and Telephone Corporation, Morinosato-Wakamiya, Atsugi-shi, Kanagawa 2430198, Japan.

出版信息

Sensors (Basel). 2012 Oct 18;12(10):14053-67. doi: 10.3390/s121014053.

DOI:10.3390/s121014053
PMID:23202035
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3545606/
Abstract

A passive pump consisting of integrated vertical capillaries has been developed for a microfluidic chip as an useful component with an excellent flow volume and flow rate. A fluidic chip built into a passive pump was used by connecting the bottoms of all the capillaries to a top surface consisting of a thin layer channel in the microfluidic chip where the thin layer channel depth was smaller than the capillary radius. As a result the vertical capillaries drew fluid cooperatively rather than independently, thus exerting the maximum suction efficiency at every instance. This meant that a flow rate was realized that exhibited little variation and without any external power or operation. A microfluidic chip built into this passive pump had the ability to achieve a quasi-steady rather than a rapidly decreasing flow rate, which is a universal flow characteristic in an ordinary capillary.

摘要

已经开发出一种由集成垂直毛细血管组成的被动泵,作为微流控芯片的有用组件,具有出色的流量和流速。通过将所有毛细管的底部连接到微流控芯片中由薄层通道组成的顶部表面,将内置有微流控芯片的流体芯片连接起来,其中薄层通道的深度小于毛细管半径。结果,垂直毛细管协作地而不是独立地吸取流体,从而在每个时刻都发挥最大的抽吸效率。这意味着实现了流量变化很小且无需任何外部动力或操作的流量。内置这种被动泵的微流控芯片能够实现准稳态而不是普通毛细管中快速下降的流量,这是一种通用的流量特性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d235/3545606/1c293a980a44/sensors-12-14053f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d235/3545606/67081f93eb23/sensors-12-14053f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d235/3545606/430b9e78fd78/sensors-12-14053f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d235/3545606/d6e2a7ab7853/sensors-12-14053f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d235/3545606/c26d06b2897a/sensors-12-14053f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d235/3545606/ba82005ffe34/sensors-12-14053f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d235/3545606/2e198f98c0b4/sensors-12-14053f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d235/3545606/fe5d0a2528b1/sensors-12-14053f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d235/3545606/1c293a980a44/sensors-12-14053f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d235/3545606/67081f93eb23/sensors-12-14053f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d235/3545606/430b9e78fd78/sensors-12-14053f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d235/3545606/d6e2a7ab7853/sensors-12-14053f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d235/3545606/c26d06b2897a/sensors-12-14053f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d235/3545606/ba82005ffe34/sensors-12-14053f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d235/3545606/2e198f98c0b4/sensors-12-14053f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d235/3545606/fe5d0a2528b1/sensors-12-14053f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d235/3545606/1c293a980a44/sensors-12-14053f8.jpg

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