中脑梗死继发发作性构音障碍和共济失调

Paroxysmal dysarthria and ataxia after midbrain infarction.

作者信息

Matsui M, Tomimoto H, Sano K, Hashikawa K, Fukuyama H, Shibasaki H

机构信息

Department of Neurology, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawaharacho, Sakyoku, Kyoto 606-8507, Japan.

出版信息

Neurology. 2004 Jul 27;63(2):345-7. doi: 10.1212/01.wnl.0000130252.69304.d2.

DOI:10.1212/01.wnl.0000130252.69304.d2

PMID:15277633

Abstract

The authors describe a patient who showed paroxysmal dysarthria and right-limb ataxia after midbrain infarction. SPECT imaging showed marked hypoperfusion in the left parietal lobe while the patient was having frequent paroxysmal attacks. After treatment with phenytoin, the symptoms and hypoperfusion in SPECT imaging improved. The authors conclude that dysfunction of the cerebellothalamocortical pathway after midbrain infarction may cause paroxysmal dysarthria and ataxia.

摘要

作者描述了一名中脑梗死患者，该患者在中脑梗死后出现发作性构音障碍和右肢共济失调。单光子发射计算机断层扫描（SPECT）成像显示，在患者频繁发作时，左顶叶有明显灌注不足。经苯妥英治疗后，症状及SPECT成像中的灌注不足情况有所改善。作者得出结论，中脑梗死后小脑丘脑皮质通路功能障碍可能导致发作性构音障碍和共济失调。