Khilnani Praveen, Sarma Devajit, Singh Reeta, Uttam Rajiv, Rajdev Shiv, Makkar Archana, Kaur Jyotinder
Apollo Center for Advanced Pediatrics, I P Apollo Hospital, New Delhi, India.
Indian J Pediatr. 2004 Jul;71(7):587-91. doi: 10.1007/BF02724117.
To study the profile and outcome of children admitted to a tertiary level pediatric intensive care unit (PICU) in India.
Prospective study of patient demographics, PRISM III scores, diagnoses, treatment, morbidity and mortality of all PICU admissions.
948 children were admitted to the PICU. Mean age was 41.48 months. Male to female ratio was 2.95:1. Mean PRISM III score on admission was 18.50. Diagnoses included respiratory (19.7%), cardiac (9.7%), neurological (17.9%), infectious (12.5%), trauma (11.7%), other surgical (8.8%).196 children (20.68%) required mechanical ventilation. Average duration of ventilation was 6.39 days. 27 children (30.7 children /1000 admissions) had acute respiratory distress syndrome. Gross mortality was 6.7% (59 patients). PRISMIII adjusted mortality was directly proportional to PRISMIII scores. 49.5% of nonsurvivors had multiorgan failure. Average length of PICU stay was 4.52 +/- 2.6 days. Complications commonly encountered were atelectasis (6.37%), accidental extubation (2%), and pneumothorax (0.9%). Incidence of nosocomial infections was 16.86%.
Our data appears to be similar with regards to PRISMIII scores and adjusted mortality, length of the PICU stay, and duration of ventilation, to previously published western data. Multiorgan failure remains a major cause of death. As expected, Dengue and malaria were common. Incidence of nosocomial infections was somewhat high. Interestingly, more boys got admitted to the PICU as compared to girls. Clearly more studies are required to assess the overall outcomes of critically ill children in India.
研究印度一家三级儿科重症监护病房(PICU)收治儿童的概况及预后。
对所有入住PICU患者的人口统计学资料、PRISM III评分、诊断、治疗、发病率和死亡率进行前瞻性研究。
948名儿童入住PICU。平均年龄为41.48个月。男女比例为2.95:1。入院时PRISM III平均评分为18.50。诊断包括呼吸系统疾病(19.7%)、心脏疾病(9.7%)、神经系统疾病(17.9%)、感染性疾病(12.5%)、创伤(11.7%)、其他外科疾病(8.8%)。196名儿童(20.68%)需要机械通气。平均通气时间为6.39天。27名儿童(每1000例入院中有30.7名)患有急性呼吸窘迫综合征。总死亡率为6.7%(59例患者)。PRISMIII校正死亡率与PRISMIII评分成正比。49.5%的非幸存者发生多器官功能衰竭。PICU平均住院时间为4.52±2.6天。常见并发症有肺不张(6.37%)、意外拔管(2%)和气胸(0.9%)。医院感染发生率为16.86%。
我们的数据在PRISMIII评分、校正死亡率、PICU住院时间和通气时间方面似乎与先前发表的西方数据相似。多器官功能衰竭仍然是主要死因。不出所料,登革热和疟疾很常见。医院感染发生率较高。有趣的是,与女孩相比,更多男孩入住PICU。显然,需要更多研究来评估印度危重症儿童的总体预后。