Hansen Marlan R, Luxford William M
Department of Otolaryngology--Head and Neck Surgery, University of Iowa, Iowa City, IA 52242, USA.
Laryngoscope. 2004 Aug;114(8):1470-4. doi: 10.1097/00005537-200408000-00028.
To determine the surgical outcomes in patients with endolymphatic sac tumors (ELSTs).
Retrospective review of patients at a referral-based otology-neurotology practice.
A review of the records from the House Ear Clinic revealed 16 patients treated for ELSTs from 1971 to 2002. This article reports the treatment outcomes for the 14 patients for whom clinical data were available.
Sensorineural hearing loss, tinnitus, and dizziness were the most common presenting signs and symptoms. Six patients presented with facial weakness, and three patients had symptoms characteristic of Menière's syndrome. One patient suffered from Von Hippel-Lindau disease. Patients underwent microsurgical removal and were followed for an average of 59.6 months. Patients that presented with normal facial function maintained excellent postoperative function, and hearing was preserved in two patients with small tumors. Two patients suffered persistent, progressive disease despite multiple attempts at microsurgical removal and radiotherapy. Both had incomplete resections of their initial tumors. A third patient developed a small recurrent tumor that was successfully managed by a second attempt at microsurgical removal.
Taken together with other reports, these results suggest that ELSTs are best managed by complete surgical resection. This can generally be accomplished with minimal additional morbidity.
确定内淋巴囊肿瘤（ELST）患者的手术疗效。
对一家以转诊为基础的耳科-神经耳科诊所的患者进行回顾性研究。
对豪斯耳科诊所的记录进行回顾，发现1971年至2002年期间有16例患者接受了ELST治疗。本文报告了14例有临床数据的患者的治疗结果。
感音神经性听力损失、耳鸣和头晕是最常见的症状和体征。6例患者出现面部无力，3例患者有梅尼埃综合征的特征性症状。1例患者患有冯·希佩尔-林道病。患者接受了显微手术切除，并平均随访59.6个月。面部功能正常的患者术后功能保持良好，2例小肿瘤患者的听力得以保留。2例患者尽管多次尝试显微手术切除和放疗，但仍患有持续性、进行性疾病。两者最初的肿瘤均未完全切除。第3例患者出现小的复发性肿瘤，通过再次显微手术切除成功治愈。
结合其他报告，这些结果表明ELST最好通过完整的手术切除来治疗。这通常可以在最小的额外发病率的情况下完成。
