Knowlton Robert C, Shih Jerry
University of Alabama at Birmingham School of Medicine, UAB Epilepsy Center, Birmingham, Alabama 35294, USA.
Epilepsia. 2004;45 Suppl 4:61-71. doi: 10.1111/j.0013-9580.2004.04012.x.
Magnetoencephalography (MEG)-also known as magnetic source imaging when combined with magnetic resonance imaging-has developed to the point that it has now entered routine clinical application. Epilepsy MEG studies show that it can accurately localize spike sources--both ictal and interictal--as compared to both direct (intracranial EEG) and indirect (imaging abnormalities) measures. Challenges remain with difficulties in detecting complex or deep sources when recording spontaneous cerebral activity. Magnetoencephalography not only provides a novel tool to localize and characterize epileptiform disturbances, it also has an important role in determining the significance of abnormalities seen on both structural and functional imaging. Combined with mapping of normal or eloquent brain function, MEG should ultimately play a major role in the totally noninvasive epilepsy surgery evaluation.
脑磁图(MEG)——当与磁共振成像结合时也被称为磁源成像——已经发展到现在已进入常规临床应用阶段。癫痫的脑磁图研究表明,与直接(颅内脑电图)和间接(成像异常)测量方法相比,它能够准确地定位发作期和发作间期的棘波源。在记录自发性脑活动时,检测复杂或深部的源仍存在困难。脑磁图不仅为定位和表征癫痫样紊乱提供了一种新工具,它在确定结构和功能成像中所见异常的意义方面也具有重要作用。结合正常或明确的脑功能图谱,脑磁图最终应在完全无创的癫痫手术评估中发挥主要作用。