脑磁图：在癫痫中的临床应用

Magnetoencephalography: clinical application in epilepsy.

作者信息

Knowlton Robert C

机构信息

UAB Epilepsy Center, Department of Neurology, University of Alabama at Birmingham School of Medicine, 1719 6th Avenue South, Suite 312, Birmingham, AL 35294, USA.

出版信息

Curr Neurol Neurosci Rep. 2003 Jul;3(4):341-8. doi: 10.1007/s11910-003-0012-2.

DOI:10.1007/s11910-003-0012-2

PMID:12930705

Abstract

Magnetoencephalography (MEG) has developed to the point that it has now entered routine clinical application. Epilepsy MEG studies show that it can accurately localize spike sources--both ictal and interictal--as compared with both directly. Limitations involve difficulties in detecting complex or deep sources when recording spontaneous cerebral activity. MEG not only provides a novel tool to localize and characterize epileptiform disturbances, it also has an important role in determining the significance of abnormalities seen on both structural and functional imaging. Ultimately, MEG should play a major role in totally noninvasive epilepsy surgery evaluation.

摘要

脑磁图（MEG）已经发展到现在进入常规临床应用阶段。癫痫的MEG研究表明，与直接检测相比，它能够准确地定位发作期和发作间期的棘波源。局限性在于记录自发性脑活动时检测复杂或深部源存在困难。MEG不仅为癫痫样紊乱的定位和特征描述提供了一种新工具，在确定结构和功能成像中所见异常的意义方面也具有重要作用。最终，MEG应在完全无创的癫痫手术评估中发挥主要作用。