Schuurman B, Meyer S, Cuesta M A, Nauta J J
Afd. Heelkunde, Academisch Ziekenhuis van de Vrije Universiteit, Amsterdam.
Ned Tijdschr Geneeskd. 1992 Aug 8;136(32):1556-60.
Recent data from literature show an increase in incidence and mortality due to soft tissue sarcoma (STS). In the Netherlands age-standardised mortality rates of soft tissue sarcoma (STS) over the period 1950-1988 show a more than fivefold increase. Males predominate over females by a factor of 1.17. Age-adjusted hospital admission rates in 1980-1988 show an increase by a factor of 1.36. The mean estimated incidence is 4.74 per 100,000 person years over a three-year period (1988-1990). The most prevalent histological types in that period were leiomyosarcoma (20.1%), malignant fibrous histiocytoma (16.2%), Kaposi's sarcoma (13.9%) and liposarcoma (13.8%). The distribution of the different histological types changes in time. The increasing incidence of Kaposi's sarcoma is due to the increasing prevalence of AIDS. Hospital admission rates for STS increased from 0.67% of admission rates for all malignant neoplasms in 1970, to 0.96% in 1988. Further epidemiological studies are needed to elucidate the increase of STS throughout the world.
近期文献数据显示,软组织肉瘤(STS)的发病率和死亡率有所上升。在荷兰,1950年至1988年期间软组织肉瘤(STS)的年龄标准化死亡率增长了五倍多。男性发病率高于女性,男女比例为1.17。1980年至1988年期间年龄调整后的住院率增长了1.36倍。在三年期间(1988年至1990年),估计平均发病率为每10万人年4.74例。该时期最常见的组织学类型为平滑肌肉瘤(20.1%)、恶性纤维组织细胞瘤(16.2%)、卡波西肉瘤(13.9%)和脂肪肉瘤(13.8%)。不同组织学类型的分布随时间变化。卡波西肉瘤发病率的上升是由于艾滋病患病率的增加。软组织肉瘤的住院率从1970年占所有恶性肿瘤住院率的0.67%升至1988年的0.96%。需要进一步开展流行病学研究,以阐明全球范围内软组织肉瘤发病率上升的情况。