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多宿主/病原体相互作用的化学生物学:化学感知与代谢互补

Chemical biology of multi-host/pathogen interactions: chemical perception and metabolic complementation.

作者信息

Palmer Andrew G, Gao Rong, Maresh Justin, Erbil W Kaya, Lynn David G

机构信息

Center for Fundamental and Applied Molecular Evolution, Departments of Chemistry and Biology, Emory University, Atlanta, Georgia 30322, USA.

出版信息

Annu Rev Phytopathol. 2004;42:439-64. doi: 10.1146/annurev.phyto.41.052002.095701.

Abstract

The xenognostic mechanisms of two multi-host pathogens, the causative agent of crown gall tumors Agrobacterium tumefaciens and the parasitic plant Striga asiatica, are compared. Both organisms are general plant pathogens and require similar information prior to host commitment. Two mechanistic strategies, chemical perception and metabolic complementation, are used to ensure successful host commitment. The critical reactions at host-parasite contact are proton and electron transfer events. Such strategies may be common among multi-host pathogens.

摘要

对两种多宿主病原体——冠瘿瘤致病因子根癌土壤杆菌和寄生植物亚洲独脚金的异源识别机制进行了比较。这两种生物体都是常见的植物病原体,在确定宿主之前需要类似的信息。它们采用了两种机制策略,即化学感知和代谢互补,以确保成功确定宿主。宿主与寄生虫接触时的关键反应是质子和电子转移事件。这种策略可能在多宿主病原体中很常见。

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