Coburn Natalie G, Chung Maureen A, Fulton John, Cady Blake
Department of Surgery, Rhode Island Hospital, Brown University School of Medicine, Providence, RI 02903, USA.
Cancer Control. 2004 Jul-Aug;11(4):222-30. doi: 10.1177/107327480401100403.
Since the 1980s, Rhode Island has achieved one of the highest mammography screening rates in the nation. The objective of this study was to determine the effect of high mammography rates on breast cancer presentation and outcomes.
Using the Rhode Island Cancer Registry, the incidence of DCIS and invasive cancer, tumor size, stage, rate of BCS and mortality from breast cancer were determined from 1987 to 2001.
Over 80% of Rhode Island women report routine mammography. From 1987 to 2001, there were 1,660 cases of DCIS and 11,301 cases of invasive breast cancer. Although the overall incidence of invasive cancer was stable, the median diameter decreased from 2 cm to 1.5 cm with a significant decrease in the incidence of stage III and IV cancers. There was an increase in BCS for women 50 to 64 years of age with stage I and II disease and for women older than 65 years with stage I disease. Disease-specific mortality decreased by 25%.
High mammography rates in Rhode Island are associated with smaller and earlier-stage breast cancers. This largely accounts for the decreased mortality from breast cancer and the increased rate of BCS.
自20世纪80年代以来，罗德岛州的乳房X线筛查率在全国名列前茅。本研究的目的是确定高乳房X线筛查率对乳腺癌的表现及治疗结果的影响。
利用罗德岛癌症登记处的数据，确定了1987年至2001年间导管原位癌（DCIS）和浸润性癌的发病率、肿瘤大小、分期、保乳手术（BCS）率以及乳腺癌死亡率。
超过80%的罗德岛州女性报告进行过常规乳房X线检查。1987年至2001年间，共有1660例导管原位癌病例和11301例浸润性乳腺癌病例。尽管浸润性癌的总体发病率保持稳定，但肿瘤中位直径从2厘米降至1.5厘米，III期和IV期癌症的发病率显著下降。50至64岁患有I期和II期疾病的女性以及65岁以上患有I期疾病的女性保乳手术率有所增加。特定疾病死亡率下降了25%。
罗德岛州的高乳房X线筛查率与更小且分期更早的乳腺癌相关。这在很大程度上解释了乳腺癌死亡率的下降以及保乳手术率的上升。
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