Xu L, Lal K, Pollock J J
School of Dental Medicine, State University of New York, Stony Brook.
Oral Microbiol Immunol. 1992 Apr;7(2):127-8. doi: 10.1111/j.1399-302x.1992.tb00524.x.
Freshly collected human parotid saliva contains 8 cationic proteins, as demonstrated by capillary electrophoresis. These proteins include lysozyme, histatin 6 and the 6 salivary histidine-rich polypeptides (HRPs 1-6). Neither histatin 2 nor histatin 4 are present in native undegraded parotid saliva but appear only after autoproteolytic degradation of the saliva. Histatin 2 appears to arise through slow degradation of HRP-1, and histatin 4 is mainly produced as a rapid breakdown product of HRP-3.
毛细管电泳显示,新采集的人腮腺唾液含有8种阳离子蛋白。这些蛋白包括溶菌酶、组蛋白6和6种富含组氨酸的唾液多肽(HRP 1-6)。天然未降解的腮腺唾液中既不存在组蛋白2也不存在组蛋白4,它们仅在唾液自蛋白水解降解后出现。组蛋白2似乎是通过HRP-1的缓慢降解产生的,而组蛋白4主要是作为HRP-3的快速分解产物产生的。