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[1例大脑中动脉分叉处细菌性动脉瘤破裂后经手术治疗的病例]

[A surgically treated case with a ruptured bacterial aneurysm of the middle cerebral arterial bifurcation following occlusion].

作者信息

Yamaguchi Shintaro, Sakata Kiyohiko, Nakayama Kenji, Orito Kimihiko, Ikeda Ayami, Arakawa Masahiro, Shigemori Minoru

机构信息

Department of Neurosurgery, Omuta City General Hospital, Fukuoka, Japan.

出版信息

No Shinkei Geka. 2004 May;32(5):493-9.

Abstract

A 56-year-old woman with aortic regurgitation (AR) developd a high fever on April 25th, 2003, followed by the sudden onset of left hemiparesis and dysarthria on May 10th, 2003. MRI and MRA showed cerebral infarction due to occlusion of the right proximal portion of the middle cerebral artery. Streptococcus was isolated from arterial blood culture at the time of admission and cardiac examination such as echocardiography revealed active infective endocarditis. Cerebral angiography on the 31st day after the onset of symptoms demonstrated a fusiform-shaped aneurysm at the occluded M2 portion of the middle cerebral artery. Despite administration of antibiotics, a small subcortical hematoma was observed in the right temporal lobe surrounding the aneurysm on the 35th day. The direct surgery of aneurysmal trapping and resection was subsequently performed to prevent rebleeding. The sylvian fissure and perianeurysmal area were strongly adherent to granulation tissue and blood clot. After exposing the aneurysm, the dilated portion of the vessel was successfully trapped and resected. Other than residual left hemiparesis, the postoperative course was uneventful. Histological examination confirmed bacterial aneurysm due to bacterial embolization originating from infective endocarditis (IE). We report a rare case having a ruptured bacterial aneurysm of the middle cerebral arterial bifurcation requiring surgery following occlusion due to bacterial embolization after sepsis and meningitis due to infective endocarditis.

摘要

一名56岁的主动脉瓣关闭不全(AR)女性于2003年4月25日出现高热,随后于2003年5月10日突然出现左侧偏瘫和构音障碍。MRI和MRA显示因大脑中动脉右侧近端闭塞导致脑梗死。入院时动脉血培养分离出链球菌,超声心动图等心脏检查显示为活动性感染性心内膜炎。症状发作后第31天的脑血管造影显示大脑中动脉闭塞的M2段有一个梭形动脉瘤。尽管使用了抗生素,但在第35天,在动脉瘤周围的右侧颞叶观察到一个小的皮质下血肿。随后进行了动脉瘤夹闭和切除术以防止再出血。外侧裂和动脉瘤周围区域与肉芽组织和血凝块紧密粘连。暴露动脉瘤后,成功夹闭并切除了血管扩张部分。除了残留的左侧偏瘫外,术后过程顺利。组织学检查证实为感染性心内膜炎(IE)引起的细菌栓塞导致的细菌性动脉瘤。我们报告了一例罕见病例,该病例大脑中动脉分叉处的细菌性动脉瘤破裂,在感染性心内膜炎引起的败血症和脑膜炎后因细菌栓塞导致闭塞,需要手术治疗。

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