Hamaguchi Hirotoshi, Kanda Fumio, Hosaka Kayo, Fujii Masahiko, Chihara Kazuo
Division of Endocrinology/Metabolism, Neurology and Hematology/Oncology, Department of Clinical Molecular Medicine, Kobe University Graduate School of Medicine.
Rinsho Shinkeigaku. 2004 Apr-May;44(4-5):263-7.
We compared images of three-dimensional stereotactic surface projections (3D-SSP) of SPECT with MRI images in spinocerebellar degeneration patients (13 olivopontocerebellar atrophy (OPCA) and 7 cortical cerebellar atrophy (CCA)). We analyzed a brain blood flow pattern with an image of statistics by 123I-IMP SPECT. In OPCA patients, a blood flow reduction was more remarkable in 3D-SSP than a degree of cerebellar atrophy in MRI. In patients with CCA, the cerebellum showed little blood flow reduction in 3D-SSP despite of apparent atrophy in MRI. Simultaneous examination both MRI and 3D-SSP might be useful for differential diagnosis of spinocerebellar degenerations.
我们将13例橄榄体脑桥小脑萎缩(OPCA)和7例皮质小脑萎缩(CCA)的脊髓小脑变性患者的单光子发射计算机断层扫描(SPECT)的三维立体定向表面投影(3D-SSP)图像与磁共振成像(MRI)图像进行了比较。我们通过123I-异碘安非他明SPECT的统计图像分析了脑血流模式。在OPCA患者中,3D-SSP中的血流减少比MRI中小脑萎缩程度更明显。在CCA患者中,尽管MRI显示明显萎缩,但3D-SSP中小脑血流减少很少。同时检查MRI和3D-SSP可能有助于脊髓小脑变性的鉴别诊断。