Waespe W, Hayek J, Wichmann W, Bader J P
Neuroradiologische Abteilung, Universitätsspital Zürich.
Schweiz Med Wochenschr. 1988 Jul 12;118(27-28):1032-8.
The sporadic form of olivo-ponto-cerebellar atrophy (OPCA) is described in 5 patients. The diagnosis was confirmed by autopsy in one patient. The OPCA can be suspected from the history and symptoms if neuroradiologic examination also demonstrates atrophy of the cerebellum and pons. OPCA is a rare but important cause of a progressive gait disturbance in the elderly patient. The differential diagnosis of atactic gait is discussed.
本文描述了5例散发性橄榄体脑桥小脑萎缩(OPCA)患者。其中1例经尸检确诊。如果神经放射学检查显示小脑和脑桥萎缩,结合病史和症状可怀疑为OPCA。OPCA是老年患者进行性步态障碍的一种罕见但重要的病因。文中讨论了共济失调步态的鉴别诊断。