Kodama Tatsuo, Tane Nobuhiro, Ohira Akihiro, Matsuoka Yotaro, Maruyama Riruke
Department of Ophthalmology, Shimane University School of Medicine, Izumo, Japan.
Jpn J Ophthalmol. 2004 Jul-Aug;48(4):415-7. doi: 10.1007/s10384-003-0065-4.
An unusual case of cavernous hemangioma coexisting with venous angioma in the ipsilateral orbit is described.
A 67-year-old woman had a mass in the lower eyelid of her right eye and proptosis. Imaging examinations showed two masses connected to each other in the extraconal space of the right orbit.
Anterior orbitotomy was performed to remove the tumors. Histopathological evaluation of the anteriorly located tumor revealed cavernous hemangioma. The posteriorly located tumor was found to be a venous angioma. Endothelial cells in both tumors showed positive immunostaining for factor VIII-related antigen and smooth muscle actin. Immunoreactivity of smooth muscle actin was more prominent in the interstitium of the posteriorly located tumor.
Coexistence of cavernous hemangioma and venous angioma in the same area suggests that they are a continuum and of the same origin.
本文描述了一例同侧眼眶海绵状血管瘤与静脉性血管瘤共存的罕见病例。
一名67岁女性右眼下眼睑有肿物并伴有眼球突出。影像学检查显示在右眼眶锥外间隙有两个相互连接的肿物。
行前路眼眶切开术切除肿瘤。对前部肿物的组织病理学评估显示为海绵状血管瘤。后部肿物为静脉性血管瘤。两个肿瘤的内皮细胞对VIII因子相关抗原和平滑肌肌动蛋白免疫染色均呈阳性。平滑肌肌动蛋白的免疫反应性在后部肿物的间质中更为显著。
同一区域内海绵状血管瘤与静脉性血管瘤共存提示它们是连续的且起源相同。