Hoffmann Jörg C, Cremer Philipp, Preiss Jan C, Ebhardt Harald, Kruschewski Martin, Buhr Heinz-Johannes, Zeitz Martin
Medizinische Klinik I mit Schwerpunkt Gastroenterologie/Infektiologie/Rheumatologie, Charité, Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Deutschland.
Digestion. 2004;70(1):45-8. doi: 10.1159/000080080. Epub 2004 Aug 3.
BACKGROUND/AIMS: We report the case of a 53-year-old man with fever and severe abdominal pain following an upper respiratory tract infection.
METHODS/RESULTS: The clinical signs, the laboratory markers, and the ultrasound findings were consistent with acute acalculous cholecystitis and he underwent cholecystectomy. Histologically the gallbladder showed vasculitis and the patient developed postoperatively a purpuric rash of the legs with transient ankle arthritis. Gastroscopy revealed prepyloric ulcers consistent with vasculitis. The patient was diagnosed as having Henoch-Schönlein purpura. Gastric ulcers as well as arthritis disappeared upon treatment with corticosteroids and proton pump inhibitors.
Taken together, Henoch-Schönlein purpura can mimic acute cholecystitis and should be considered as a rare differential diagnosis of acute cholecystitis.
背景/目的:我们报告一例53岁男性,在上呼吸道感染后出现发热和严重腹痛。
方法/结果:临床体征、实验室指标及超声检查结果均符合急性非结石性胆囊炎,遂行胆囊切除术。组织学检查显示胆囊存在血管炎,患者术后出现腿部紫癜性皮疹及短暂性踝关节关节炎。胃镜检查发现符合血管炎的幽门管溃疡。该患者被诊断为过敏性紫癜。经皮质类固醇和质子泵抑制剂治疗后,胃溃疡及关节炎消失。
综上所述,过敏性紫癜可酷似急性胆囊炎,应被视为急性胆囊炎一种罕见的鉴别诊断。