van der Boon F, Groeneweg M
Medisch Centrum Rijnmond-Zuid, locatie Zuider, afd. Kindergeneeskunde, Groene Hilledijk 315, 3075 EA Rotterdam.
Ned Tijdschr Geneeskd. 2005 Nov 5;149(45):2522-6.
2 girls with abdominal pain, aged 7 and 9 years, were admitted and underwent extensive evaluation: the first girl underwent colonoscopy and the second appendectomy, in which a negative appendix was removed. After 6 and 14 days, respectively, they developed skin lesions that did not disappear on pressure, characteristic of Henoch-Schönlein purpura (HSP). They recovered after treatment with prednisone. HSP is a systemic vasculitis, which can be diagnosed by its characteristic purpura of the skin. Diagnosis is more difficult if the patient does not present with skin lesions. HSP presenting with acute abdominal pain as an initial symptom can give rise to unnecessary additional investigation and even laparotomy. Apart from the other clinical features of HSP, i.e. bloody stools, oligo-articular arthritis and (microscopic) haematuria, diagnosis can be made earlier if biopsies of the normal skin or duodenum are taken and assessed for IgA depositions. Treatment of the abdominal pain with corticosteroids can be considered.
两名分别为7岁和9岁的女童因腹痛入院并接受了全面评估:第一名女童接受了结肠镜检查,第二名女童接受了阑尾切除术,切除的阑尾未见异常。分别在6天和14天后,她们出现了受压不褪色的皮肤病变,这是过敏性紫癜(HSP)的特征。她们在接受泼尼松治疗后康复。HSP是一种系统性血管炎,可通过其特征性的皮肤紫癜进行诊断。如果患者没有皮肤病变,诊断会更加困难。以急性腹痛为首发症状的HSP可能会导致不必要的进一步检查甚至剖腹手术。除了HSP的其他临床特征,即血便、少关节性关节炎和(镜下)血尿外,如果对正常皮肤或十二指肠进行活检并评估IgA沉积情况,可以更早地做出诊断。可以考虑用皮质类固醇治疗腹痛。