Gao Yu-Ping, Zhu Jian-Shan, Zheng Wen-Jun
Department of Pathology, Affiliated Renji Hospital, Shanghai Second Medical University, 145 Shandong (c) Road, Shanghai 200001, China.
World J Gastroenterol. 2004 Sep 1;10(17):2616-7. doi: 10.3748/wjg.v10.i17.2616.
To analyze the clinicopathological features of Brunner's gland adenoma of the duodenum.
A rare case of Brunner's gland adenoma of the duodenum was described and related literature was reviewed.
Brunner's gland adenoma of the duodenum appeared to be nodular hyperplasia of the normal Brunner's gland with an unusual admixture of normal tissues, including ducts, adipose tissue and lymphoid tissue. We suggested that it might be designated as a duodenal hamartoma rather than a true neoplasm.
The most common location of the lesion is the posterior wall of the duodenum near the junction of its first and second portions. It can result in gastrointestinal hemorrhage and duodenal obstruction. Endoscopic polypectomy is a worthy treatment for benign Brunner's gland adenomas, as malignant changes in these tumors have never been proven.
分析十二指肠布伦纳腺腺瘤的临床病理特征。
描述1例罕见的十二指肠布伦纳腺腺瘤病例并复习相关文献。
十二指肠布伦纳腺腺瘤表现为正常布伦纳腺的结节样增生,伴有包括导管、脂肪组织和淋巴组织在内的正常组织的异常混合。我们认为它可能应被指定为十二指肠错构瘤而非真正的肿瘤。
病变最常见的部位是十二指肠第一和第二部分交界处附近的后壁。它可导致胃肠道出血和十二指肠梗阻。内镜下息肉切除术是治疗良性布伦纳腺腺瘤的一种值得采用的方法,因为这些肿瘤从未被证实会发生恶变。