Mochizuki Tetsuya, Fujikuni Nobuaki, Nakadoi Koichi, Nakahara Masahiro, Tanabe Kazuaki, Yonehara Shuji, Noriyuki Toshio
Department of Surgery, Onomichi General Hospital, Onomichi, Hiroshima, Japan.
Department of Gastroenterology, Onomichi General Hospital, Onomichi, Hiroshima, Japan.
Surg Case Rep. 2019 Nov 14;5(1):179. doi: 10.1186/s40792-019-0732-4.
Duodenal carcinoma originating in Brunner's gland is rare. Herein, we report a case of duodenal carcinoma arising from Brunner's gland in a 63-year-old man.
On diagnostic imaging, the lesion presented as a non-invasive carcinoma; the patient also had uncontrolled diabetes and liver cirrhosis. Hence, we decided to perform partial duodenectomy to reduce operative stress. Pathological examination revealed that the tumor consisted of tissue from Brunner's gland. Additionally, the carcinoma cells were strongly positive for Mucin-6 protein, which is an epithelial marker of Brunner's gland. The patient's post-operative course was uneventful, and he has been well for 2 years after the surgery.
This a rare case of an adenocarcinoma arising from Brunner's gland of the duodenum that was resected by duodenectomy.
起源于布伦纳腺的十二指肠癌很罕见。在此，我们报告一例63岁男性起源于布伦纳腺的十二指肠癌病例。
在诊断性影像学检查中，该病变表现为非浸润性癌；患者还患有未得到控制的糖尿病和肝硬化。因此，我们决定行十二指肠部分切除术以减轻手术应激。病理检查显示肿瘤由布伦纳腺组织构成。此外，癌细胞的黏蛋白-6蛋白呈强阳性，该蛋白是布伦纳腺的一种上皮标志物。患者术后恢复顺利，术后2年情况良好。
这是一例罕见的起源于十二指肠布伦纳腺的腺癌，通过十二指肠切除术得以切除。
