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手辅助后腹腔镜肾切除术用于活体肾移植:初步44例报告

Hand-assisted retroperitoneoscopic nephrectomy for living kidney transplantation: initial 44 cases.

作者信息

Tsuchiya Norihiko, Iinuma Masahiro, Habuchi Tomonori, Ohyama Chikara, Matsuura Shinobu, Sato Kazunari, Satoh Shigeru, Kato Tetsuro

机构信息

Department of Urology, Akita University School of Medicine, Akita, Japan.

出版信息

Urology. 2004 Aug;64(2):250-4. doi: 10.1016/j.urology.2004.03.043.

Abstract

OBJECTIVES

To report our technique and early results of hand-assisted retroperitoneoscopic nephrectomy (HARN) for living donor transplantation and to assess its feasibility.

METHODS

HARN was effectively and safely performed on 44 donors from July 2001 to September 2003 at Akita University Medical Center. We describe our techniques and experiences with HARN and compare the early results with those of 27 cases of open donor nephrectomy at our institution.

RESULTS

The mean operating time was 260 minutes (range 173 to 445), the mean estimated blood loss was 249 mL (range 15 to 967), and the mean warm ischemia time was 2.2 minutes (range 0.8 to 6.4). These parameters were similar to those of open donor nephrectomy. Intraoperative and postoperative complications occurred in 1 (2.3%) and 2 (4.6%) cases, respectively, but they were all minor. HARN was converted to open nephrectomy in 1 case (2.3%) because of uncontrollable bleeding. All HARN donors were ambulant within 2 days postoperatively and could initiate oral intake on the first postoperative day. Regarding graft function, 41 recipients (93.2%) had an immediate onset of diuresis and 3 (6.8%) had delayed renal function. The serum creatinine 7 days and 1 month postoperatively was not significantly different between the HARN group and the open nephrectomy group.

CONCLUSIONS

HARN for living donors is one excellent option for donor nephrectomy because the procedure does not require intraperitoneal manipulation, thus reducing the risk of abdominal visceral injury, and also because of the minimal warm ischemia time owing to rapid extraction of the kidney with hand assistance.

摘要

目的

报告我们在活体供肾移植中采用手辅助后腹腔镜肾切除术(HARN)的技术及早期结果,并评估其可行性。

方法

2001年7月至2003年9月,秋田大学医学中心对44例供体有效且安全地实施了HARN。我们描述了HARN的技术和经验,并将早期结果与本院27例开放性供肾切除术的结果进行比较。

结果

平均手术时间为260分钟(范围173至445分钟),平均估计失血量为249毫升(范围15至967毫升),平均热缺血时间为2.2分钟(范围0.8至6.4分钟)。这些参数与开放性供肾切除术相似。术中及术后并发症分别发生1例(2.3%)和2例(4.6%),但均为轻微并发症。1例(2.3%)因出血无法控制而转为开放性肾切除术。所有接受HARN的供体术后2天内即可下床活动,术后第1天即可开始经口进食。关于移植肾功能,41例受者(93.2%)术后立即出现利尿,3例(6.8%)肾功能延迟恢复。HARN组与开放性肾切除术组术后7天和1个月时的血清肌酐水平无显著差异。

结论

对于活体供肾者,HARN是肾切除术的一个极佳选择,因为该手术无需进行腹腔内操作,从而降低了腹部脏器损伤的风险,而且由于在手部辅助下能快速取出肾脏,热缺血时间最短。

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