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巨大海绵状肝血管瘤:手术方式对预后的影响。

Giant cavernous liver hemangiomas: effect of operative approach on outcome.

作者信息

Lerner Susan M, Hiatt Jonathan R, Salamandra Johanna, Chen Pauline W, Farmer Douglas G, Ghobrial Rafik M, Busuttil Ronald W

机构信息

Department of Surgery, Pennsylvania State Milton S. Hershey Medical Center, Hershey, USA.

出版信息

Arch Surg. 2004 Aug;139(8):818-21; discussion 821-3. doi: 10.1001/archsurg.139.8.818.

Abstract

HYPOTHESIS

The choice of operative technique for resection of giant cavernous hepatic hemangiomas has an effect on outcome.

DESIGN

Case series.

SETTING

Tertiary hepatobiliary surgery-liver transplantation service.

PATIENTS AND INTERVENTIONS

Fifty-two adult patients who underwent resection of symptomatic hepatic hemangiomas (38 [73%] in the right lobe; average diameter, 10.9 cm) by means of lobectomy or enucleation, with or without Pringle inflow occlusion.

MAIN OUTCOME MEASURES

Blood transfusion, morbidity, mortality, and length of hospitalization.

RESULTS

Patient age and sex and the size of hemangiomas were similar for patients who underwent lobectomy and enucleation. Right-lobe lesions were more often treated by enucleation, and inflow occlusion was used more frequently; transfusion requirements and length of hospitalization were similar for both techniques. Complications were more frequent after lobectomy. There were no deaths. In the latter years of the series, enucleation was used in 22 (63%) and inflow occlusion in 24 (69%) of 35 patients.

CONCLUSIONS

Outcome is related to the operative approach used for resection of giant cavernous liver hemangiomas. Although lobectomy and enucleation are curative, enucleation offers greater preservation of normal hepatic parenchyma and fewer complications and is the preferred technique for suitable lesions.

摘要

假设

巨大海绵状肝血管瘤切除手术技术的选择对手术结果有影响。

设计

病例系列研究。

地点

三级肝胆外科-肝移植服务中心。

患者与干预措施

52例成年患者因有症状的肝血管瘤接受了肝叶切除术或摘除术(右叶38例[73%];平均直径10.9厘米),手术中使用或未使用Pringle血流阻断法。

主要观察指标

输血情况、发病率、死亡率及住院时间。

结果

接受肝叶切除术和摘除术的患者在年龄、性别及血管瘤大小方面相似。右叶病变更常采用摘除术治疗,且更频繁地使用血流阻断法;两种技术的输血需求和住院时间相似。肝叶切除术后并发症更常见。无死亡病例。在该系列研究的后期,35例患者中有22例(63%)采用摘除术,24例(69%)采用血流阻断法。

结论

手术结果与巨大海绵状肝血管瘤切除所采用的手术方式有关。虽然肝叶切除术和摘除术都可治愈疾病,但摘除术能更好地保留正常肝实质,并发症更少,是适合病变的首选技术。

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