Rana S V, Bhasin D K, Naik N, Subhiah M, Ravinder Pal
Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh.
Trop Gastroenterol. 2004 Jan-Mar;25(1):18-20.
Lactase activity with age has been reported in a wide variety of population globally. However, most of these studies in human have ignored to assess age stratified lactose maldigestion. Therefore, the present study was planned to determine lactose maldigestion in different age groups of north Indians adults. Two hundred apparently healthy north Indians (age rage 10-80 years) were subjected to a 50g lactose hydrogen breath test by standard method using a Model 12 Microlyzer from Quintron, USA. The percentage of lactose maldigestion was calculated for different age groups with an interval of 10 years. The results of this study revealed that the frequency of lactose maldigestion did not differ significantly among the age groups. Thus, this study suggests that lactose maldigestion is not associated with age stratification among north Indians.
全球范围内,已有关于乳糖酶活性随年龄变化的报道,涉及众多不同人群。然而,大多数针对人类的此类研究都忽略了评估按年龄分层的乳糖消化不良情况。因此,本研究旨在确定北印度成年人群不同年龄组中的乳糖消化不良情况。选取了200名表面健康的北印度人(年龄范围为10 - 80岁),采用美国Quintron公司的12型微量分析仪,通过标准方法进行50克乳糖氢呼气试验。计算了不同年龄组(间隔为10年)的乳糖消化不良百分比。本研究结果显示,各年龄组之间乳糖消化不良的发生率无显著差异。因此,本研究表明,北印度人群中乳糖消化不良与年龄分层无关。