Salvà Antoni, Corman Bruno, Andrieu Sandrine, Salas Jordi, Vellas Bruno
Institut Catala de l'Envelliment, Fundació Universitat Autónoma de Barcelona, St. Antoni M. Claret 171, 08041 Barcelona, Spain.
J Gerontol A Biol Sci Med Sci. 2004 Jul;59(7):724-9. doi: 10.1093/gerona/59.7.m724.
Malnutrition, considered for the purpose of the present data set as undernutrition, is a major risk factor of mortality in elderly people. Such protein-energy malnutrition should be detected as soon as possible. Once established, this malnutrition state must be corrected by appropriate diet, supplementation, artificial nutrition, or therapeutic treatment. If carried out well, these interventions should reduce the risk of mortality and, for some diseases such as degenerative diseases, may postpone morbidity and dependence. The efficiency of nutritional interventions has already been evaluated by different means including the measurement of anthropometric and laboratory parameters. However, in the absence of a consensus on the use of these parameters, comparison between studies and even effectiveness of the proposed treatment are frequently unconvincing. The relevance of the most common markers used in epidemiologic studies on malnutrition and nutritional interventions in elderly persons was studied for establishing a minimum data set. The aim of this task force was to provide investigators and operators in the field of clinical nutrition with clear and expert validated clinical outcomes allowing them to design and set up conclusive trials.
在本数据集里，营养不良被视为营养不足，它是老年人死亡的主要风险因素。这种蛋白质 - 能量营养不良应尽早被检测出来。一旦确诊，必须通过适当的饮食、补充剂、人工营养或治疗手段来纠正这种营养不良状态。如果实施得当，这些干预措施应能降低死亡风险，对于某些疾病，如退行性疾病，还可能延缓发病和失能。营养干预的效果已经通过不同方式进行了评估，包括测量人体测量学和实验室参数。然而，由于在这些参数的使用上缺乏共识，研究之间的比较乃至所提议治疗方法的有效性往往难以令人信服。为了建立一个最小数据集，我们研究了在老年人营养不良和营养干预的流行病学研究中使用的最常见标志物的相关性。该特别工作组的目的是为临床营养领域的研究人员和从业者提供经专家验证的明确临床结果，以便他们设计并开展结论性试验。
