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揭示人类胰岛素抵抗的细胞机制:磁共振波谱学的新见解

Unraveling the cellular mechanism of insulin resistance in humans: new insights from magnetic resonance spectroscopy.

作者信息

Shulman Gerald I

机构信息

Departments of Internal Medicine and Cellular and Molecular Physiology, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

出版信息

Physiology (Bethesda). 2004 Aug;19:183-90. doi: 10.1152/physiol.00007.2004.

Abstract

Insulin resistance plays a major role in the pathogenesis of type 2 diabetes, yet despite much research the underlying mechanism responsible for it is poorly understood. In this review, some recent advances in the understanding of insulin resistance in humans that have been made by using magnetic resonance spectroscopy are discussed.

摘要

胰岛素抵抗在2型糖尿病的发病机制中起主要作用,然而,尽管进行了大量研究,但其潜在机制仍知之甚少。在这篇综述中,我们将讨论利用磁共振波谱技术在人类胰岛素抵抗研究方面取得的一些最新进展。

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