Rennie C A, Chowdhury S, Khan J, Rajan F, Jordan K, Lamb R J, Vivian A J
Department of Ophthalmology, West Suffolk Hospital, Bury St Edmunds, Suffolk IP33 2QZ, UK.
Eye (Lond). 2005 Apr;19(4):396-9. doi: 10.1038/sj.eye.6701508.
To estimate the prevalence of posterior embryotoxon (PE) in the general ophthalmic clinic and to identify any features of PE that suggest that it is pathological rather than physiological.
Over 700 consecutive patients of all ages were examined with the slit lamp during their routine eye clinic appointment. Patients with posterior embryotoxon were invited to return for full ocular examination including keratometry, corneal topography, and gonioscopy.
In all, 49 out of 723 patients were found to have PE. This gives a prevalence of 6.8% with an age range of 18 months to 95 years. There was a higher prevalence in the younger age group of 22.5% (age range 18 months to 20 years) compared to 5.9% in the older age range (21-95 years). A total of 29 patients with PE returned for further examination. Six patients had glaucoma (two with Axenfeld's syndrome and one with aniridia), and one had ocular hypertension. In all, 20 patients had bilateral PE on slit-lamp examination, which increased to 24 with gonioscopy. The majority of the PE was seen temporally (97.9%) and limited to a few clock hours. Gonioscopy showed that eight patients with PE had associated inferior pigmentation of schwalbes line.
This large series found the prevalence of PE the general ophthalmic clinic to be 6.8%. Its presence should prompt careful anterior segment examination, including gonioscopy, to identify any associated abnormalities that may carry a risk of glaucoma. Children should also be assessed for any associated systemic or genetic abnormality.
评估普通眼科门诊中后胚胎环(PE)的患病率,并确定PE提示其为病理性而非生理性的任何特征。
在常规眼科门诊预约期间,使用裂隙灯对700多名各年龄段的连续患者进行检查。邀请患有后胚胎环的患者回来进行全面的眼部检查,包括角膜曲率测量、角膜地形图检查和前房角镜检查。
在723名患者中,共发现49例患有PE。患病率为6.8%,年龄范围为18个月至95岁。较年轻年龄组(18个月至20岁)的患病率较高,为22.5%,而较年长年龄组(21 - 95岁)的患病率为5.9%。共有29例患有PE的患者回来进行进一步检查。6例患者患有青光眼(2例患有Axenfeld综合征,1例患有无虹膜症),1例患有高眼压症。在裂隙灯检查中,共有20例患者双眼患有PE,在前房角镜检查中增加到24例。大多数PE见于颞侧(97.9%),且局限于几个钟点范围。前房角镜检查显示,8例患有PE的患者伴有施瓦贝线下方色素沉着。
这个大样本系列研究发现普通眼科门诊中PE的患病率为6.8%。其存在应促使进行仔细的眼前节检查,包括前房角镜检查,以识别任何可能存在青光眼风险的相关异常情况。还应对儿童评估是否存在任何相关的全身或遗传异常情况。