Al-Bdour Muawyah D, Al-Till Maha I, Idrees Ghaida M, Abu Samra Khawla M
Department of Ophthalmology, Jordan University Hospital, Amman, Jordan.
Acta Ophthalmol. 2008 Nov;86(7):755-7. doi: 10.1111/j.1755-3768.2008.01258.x. Epub 2008 Aug 27.
This study aimed to estimate the prevalence of pseudoexfoliation syndrome (PXS) and analyse its association with particular ocular diseases in patients attending the Department of Ophthalmology at Jordan University Hospital.
A total of 1195 consecutive patients, aged 40-90 years, who attended the Department of Ophthalmology at Jordan University Hospital between December 2005 and March 2007 were included in the study. Each patient underwent complete ophthalmic evaluation, including: relevant history; visual acuity testing; slit-lamp examination, applanation tonometry, gonioscopy and dilated fundus examination. Patients with typical pseudoexfoliative material on the anterior lens surface and/or the pupillary margin in either or both eyes were labelled as having PXS.
Of the 1195 patients, 9.1% had pseudoexfoliation (PXF). Their mean age was 68.3 years (standard deviation [SD] 9.57). The prevalence of PXS had a tendency to increase with age but had no sex predilection. Pseudoexfoliation was bilateral in 65.7% of cases. It was significantly associated with cataract, glaucoma and phacodenesis. Of the eyes with PXF, 92.1% had cataract, 33.1% had glaucoma and 7.9% had phacodenesis.
Although this study was not population-based, its findings increase our knowledge of PXS in a Middle Eastern country. Few data on PXS are available from this part of the world.
本研究旨在评估约旦大学医院眼科就诊患者中假性剥脱综合征(PXS)的患病率,并分析其与特定眼部疾病的关联。
2005年12月至2007年3月期间在约旦大学医院眼科就诊的1195例年龄在40至90岁之间的连续患者纳入本研究。每位患者均接受了全面的眼科评估,包括:相关病史;视力测试;裂隙灯检查、压平眼压测量、前房角镜检查和散瞳眼底检查。双眼任一或双眼的晶状体前表面和/或瞳孔缘有典型假性剥脱物质的患者被标记为患有PXS。
在1195例患者中,9.1%患有假性剥脱(PXF)。他们的平均年龄为68.3岁(标准差[SD]9.57)。PXS的患病率有随年龄增加的趋势,但无性别倾向。65.7%的病例中假性剥脱为双侧性。它与白内障、青光眼和晶状体不全显著相关。在患有PXF的眼中,92.1%患有白内障,33.1%患有青光眼,7.9%患有晶状体不全。
尽管本研究并非基于人群,但研究结果增加了我们对中东国家PXS的了解。世界上这个地区关于PXS的可用数据很少。