Rao Rashad Qamar, Arain Tariq Mehmood, Ahad Muhammad Ali
Department of Ophthalmology, South Wing St Thomas' Hospital, London SE1 7EH, UK.
BMC Ophthalmol. 2006 Jun 22;6:27. doi: 10.1186/1471-2415-6-27.
Pseudoexfoliation syndrome (PXS) is the most common identifiable cause of secondary glaucoma, the prevalence of which varies considerably among different ethnicities. The aim of this study was to assess the prevalence of pseudoexfoliation syndrome in Pakistan.
A prospective study conducted in the period from January 2003 to June 2004 in a teaching hospital serving a population of about 7.6 million. 1860 patients aged 45 or above attending the general ophthalmic clinics were recruited for this study. A detailed evaluation including ophthalmic and general history, slit lamp biomicroscopy, intraocular pressure measurement, gonioscopy and dilated eye examination was performed on all patients.
120(6.45%) subjects were found to have PXS with a male to female ratio of 1.5:1. All 120 (100%) cases were bilateral and 48(40%) patients had high intraocular pressure.
To the best of our knowledge, this is the first study conducted in a Pakistani population to determine the prevalence of PXS. The prevalence rate of 6.45% is similar to other studies conducted in south Asia, however all cases were bilateral and quite a high percentage of patients had high intra-ocular pressure.
假性剥脱综合征（PXS）是继发性青光眼最常见的可识别病因，其患病率在不同种族中差异很大。本研究的目的是评估巴基斯坦假性剥脱综合征的患病率。
2003年1月至2004年6月在一家为约760万人口服务的教学医院进行了一项前瞻性研究。本研究招募了1860名年龄在45岁及以上、到普通眼科门诊就诊的患者。对所有患者进行了详细评估，包括眼科和全身病史、裂隙灯生物显微镜检查、眼压测量、前房角镜检查和散瞳眼底检查。
发现120名（6.45%）受试者患有PXS，男女比例为1.5:1。所有120例（100%）均为双侧患病，48例（40%）患者眼压升高。
据我们所知，这是在巴基斯坦人群中进行的第一项确定PXS患病率的研究。6.45%的患病率与在南亚进行的其他研究相似，然而所有病例均为双侧患病，且相当高比例的患者眼压升高。
