Palomäki Outi, Jansson Miia, Huhtala Heini, Kirkinen Pertti
Department of Obstetrics and Gynecology, Tampere University Hospital, Finland.
Am J Perinatol. 2004 Aug;21(6):347-53. doi: 10.1055/s-2004-831879.
The purpose of this study was to evaluate the effect of acute tocolysis on severely pathological cardiotocographic (CTG) readings during the first stage of labor. Seventy-three consecutive parturients with full-term pregnancy were treated by acute tocolysis with a beta-mimetic agent after recognition of severe CTG abnormality in the first stage of labor. The main outcome measures were normalization or persistence of the CTG pattern after tocolysis. Risk factors with regard to CTG effect of tocolysis were also evaluated. In 67% of cases the CTG pattern normalized at a mean of 4 minutes after the beginning of intravenous tocolysis. No characteristic feature of the parturient, labor course, CTG abnormality, or the parameters of uterine contractive activity was found to be a predictive factor with regard to the CTG effect of tocolysis. No adverse effects of tocolytic therapy were found. Tocolysis with a beta-mimetic agent is an effective method to normalize the CTG pattern during the first stage of labor, even in cases without uterine hypertonicity.
本研究的目的是评估急性宫缩抑制对产程第一阶段严重异常的胎心监护（CTG）读数的影响。73例足月妊娠产妇在产程第一阶段被识别出严重CTG异常后，接受了β-拟交感神经药物的急性宫缩抑制治疗。主要观察指标是宫缩抑制后CTG图形的恢复正常或持续异常。同时也评估了与宫缩抑制CTG效应相关的危险因素。67%的病例在静脉注射宫缩抑制剂开始后平均4分钟时CTG图形恢复正常。未发现产妇特征、产程、CTG异常或子宫收缩活动参数中的任何特征可作为宫缩抑制CTG效应的预测因素。未发现宫缩抑制治疗的不良反应。使用β-拟交感神经药物进行宫缩抑制是使产程第一阶段CTG图形恢复正常的有效方法，即使在没有子宫高张的情况下也是如此。
