[卡方检验和确切检验在哈迪-温伯格平衡检验中的应用]
[Application of chi-square test and exact test in Hardy-Weinberg equilibrium testing].
作者信息
Huang Dai-Xin, Yang Qing-En
机构信息
Faculty of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030,China.
出版信息
Fa Yi Xue Za Zhi. 2004;20(2):116-9.
PMID:15311526
Abstract
This article review the application of chi-square test of various data handling methods and exact test in Hardy-Weinberg equilibrium testing of human genetic marker in population genetics. The importance of HWE-exact test in multiallelic system was emphasized, especially in the study of forensic VNTR and STR typing.
摘要
本文综述了卡方检验的各种数据处理方法以及精确检验在群体遗传学中人类遗传标记的哈迪-温伯格平衡检验中的应用。强调了哈迪-温伯格平衡精确检验在多等位基因系统中的重要性，尤其是在法医VNTR和STR分型研究中。
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