Pramesh C S, Madur Bhulaxmi P, Raina Sudip, Desai Sangeeta B, Mistry Rajesh C
Division of Thoracic Surgery, Department of Surgical Oncology and Pathology, Tata Memorial Hospital, Mumbai, India.
Ann Thorac Cardiovasc Surg. 2004 Jun;10(3):187-90.
Angiosarcoma is a rare, highly malignant tumor arising from endothelial cells of small blood vessels. They usually occur in the skin, deep soft tissues, breast and liver. Pleural angiosarcomas are extremely rare and are restricted to case reports in medical literature. It is very difficult to distinguish them from malignant mesotheliomas on clinical, radiological and even histopathological features. Immunohistochemistry is valuable in making the diagnosis, showing negative reactivity for mesothelial markers and positivity for vascular markers. Prognosis is generally dismal except in occasional cases where the disease is localized and amenable for surgical resection. We report a 55-year-old man who presented to us with chest pain, cough and hemoptysis and was diagnosed to have a pleural angiosarcoma.
血管肉瘤是一种罕见的、高度恶性的肿瘤，起源于小血管的内皮细胞。它们通常发生于皮肤、深部软组织、乳腺和肝脏。胸膜血管肉瘤极为罕见，在医学文献中仅有病例报告。根据临床、放射学甚至组织病理学特征，很难将它们与恶性间皮瘤区分开来。免疫组织化学在诊断中具有重要价值，显示对间皮标志物呈阴性反应，对血管标志物呈阳性反应。除了少数疾病局限且适合手术切除的病例外，总体预后很差。我们报告了一名55岁男性，他因胸痛、咳嗽和咯血前来就诊，被诊断为胸膜血管肉瘤。
