Sedhai Yub Raj, Basnyat Soney, Golamari Reshma, Koirala Ajay, Yuan Mengdan
VCU School of Medicine, Richmond, VA, USA.
St. Mary Mercy Hospital, Livonia, MI, USA.
SAGE Open Med Case Rep. 2020 Feb 10;8:2050313X20904595. doi: 10.1177/2050313X20904595. eCollection 2020.
Primary pleural angiosarcoma is an exceptionally rare malignancy of pleura originating from the vascular endothelial cells. Here, we present a 70-year-old African-American female who presented with 1-month history of dyspnea on exertion, loss of appetite, and loss of weight along with left-sided pleuritic chest pain. Evaluation revealed hemorrhagic pleural effusion in the left pleural cavity. Computed tomography of the chest performed after therapeutic thoracocentesis revealed left upper lobe lung mass along with multiple nodules in right lung. Mass was biopsied at video-assisted thoracoscopy. Histopathology was consistent with high-grade angiosarcoma. Endothelial origin of the tumor cells was confirmed with positive immunohistochemical staining with CD31 antibodies. Our patient was diagnosed with primary pleural angiosarcoma metastatic to the lung. She opted for palliative care and had a rapidly declining clinical course and expired within 5 weeks of the diagnosis. Here, we present a case report and review the relevant literature.
原发性胸膜血管肉瘤是一种极为罕见的起源于血管内皮细胞的胸膜恶性肿瘤。在此，我们报告一例70岁的非裔美国女性，她有1个月的劳力性呼吸困难、食欲减退、体重减轻病史，伴有左侧胸膜炎性胸痛。评估发现左侧胸腔有血性胸腔积液。治疗性胸腔穿刺术后进行的胸部计算机断层扫描显示左上叶肺肿块以及右肺多个结节。在电视辅助胸腔镜下对肿块进行了活检。组织病理学与高级别血管肉瘤一致。肿瘤细胞的内皮起源通过CD31抗体免疫组化染色阳性得到证实。我们的患者被诊断为原发性胸膜血管肉瘤肺转移。她选择了姑息治疗，临床病程迅速恶化，诊断后5周内死亡。在此，我们报告一例病例并复习相关文献。
