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体外受精-胚胎移植反复失败患者在体外受精-胚胎移植前采用父源淋巴细胞进行免疫治疗。

Immunotherapy with paternal lymphocytes preceding in vitro fertilization-embryo transfer for patients with repeated failure of embryo transfer.

作者信息

Hasegawa I, Tani H, Takakuwa K, Yamada K, Kanazawa K, Tanaka K

机构信息

Department of Obstetrics and Gynecology, Niigata University School of Medicine, Japan.

出版信息

Fertil Steril. 1992 Feb;57(2):445-7. doi: 10.1016/s0015-0282(16)54862-6.

Abstract

Immunotherapy with paternal lymphocytes for unexplained recurrent aborters was applied, preceding IVF-ET, for infertile women with repeated failure of ET. In one patient showing close histocompatibility with the husband, the subsequent new IVF-ET was successful under positive MLR-blocking antibody induced by immunotherapy.

摘要

对于不明原因复发性流产患者,在体外受精-胚胎移植(IVF-ET)之前,采用丈夫淋巴细胞免疫疗法,用于胚胎移植反复失败的不孕女性。在一名与丈夫组织相容性相近的患者中,在免疫疗法诱导的阳性混合淋巴细胞反应(MLR)阻断抗体作用下,随后进行的新IVF-ET取得成功。

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