Pico-Alfonso Maria A, Garcia-Linares M Isabel, Celda-Navarro Nuria, Herbert Joe, Martinez Manuela
Department of Psychobiology, University of Valencia, Valencia, Spain.
Biol Psychiatry. 2004 Aug 15;56(4):233-40. doi: 10.1016/j.biopsych.2004.06.001.
Although intimate partner violence (IPV) has a great impact on women's health, few studies have assessed the consequences on physiologic responses.
Women abused by their intimate male partners either physically (n = 70) or psychologically (n = 46) were compared with nonabused control women (n = 46). Information about sociodemographic characteristics, smoking, pharmacologic treatment, lifetime history of victimization (childhood and adulthood), and mental health status (depression, anxiety, and posttraumatic stress disorder, PTSD) was obtained through structured interviews. Saliva samples were collected at 8 am and 8 pm for 4 consecutive days to determine morning and evening basal levels of cortisol and dehydroepiandrosterone (DHEA).
Women who were victims of IPV had more severe symptoms of depression, anxiety, and incidence of PTSD and higher levels of evening cortisol and morning and evening DHEA compared with control women. Intimate partner violence was the main factor predicting the alterations in hormonal levels after controlling for age, smoking, pharmacologic treatment, and lifetime history of victimization. Mental health status did not have a mediating effect on the impact of IPV on hormonal levels.
This study shows that both physical and psychological IPV have a significant impact on the endocrine systems of women.
尽管亲密伴侣暴力（IPV）对女性健康有很大影响，但很少有研究评估其对生理反应的后果。
将遭受亲密男性伴侣身体虐待（n = 70）或心理虐待（n = 46）的女性与未受虐待的对照女性（n = 46）进行比较。通过结构化访谈获取有关社会人口学特征、吸烟、药物治疗、受害终身史（童年和成年）以及心理健康状况（抑郁、焦虑和创伤后应激障碍，PTSD）的信息。连续4天每天上午8点和晚上8点采集唾液样本，以测定皮质醇和脱氢表雄酮（DHEA）的早晚基础水平。
与对照女性相比，IPV受害者有更严重的抑郁、焦虑症状和PTSD发生率，且晚上皮质醇以及上午和晚上DHEA水平更高。在控制年龄、吸烟、药物治疗和受害终身史后，亲密伴侣暴力是预测激素水平变化的主要因素。心理健康状况对IPV对激素水平的影响没有中介作用。
本研究表明，身体和心理层面的IPV均对女性内分泌系统有显著影响。
