De Chazeron I, Raboisson P, Dallel R
INSERM E 0216, Neurobiologie de La Douleur Trigéminale, Faculté de Chirurgie Dentaire, 11 Bd Charles de Gaulle, 63000 Clermont-Ferrand, France.
Neuroscience. 2004;127(4):921-8. doi: 10.1016/j.neuroscience.2004.06.005.
The organization of the efferent projections from the spinal trigeminal nucleus oralis (Sp5O) to the diencephalon was studied in the rat using the anterograde tracer Phaseolus vulgaris leucoagglutinin. The present study confirms the existence of trigemino-thalamic pathways originating from the Sp5O and details their distribution. The main diencephalic targets of the Sp5O are the ventral posteromedial thalamic nucleus (VPM), the posterior thalamic nuclei (Po) and the ventral part of the zona incerta (ZIv), contralaterally, and the parvicellular part of the ventral posterior thalamic nucleus (VPpc), bilaterally. The distribution of these projections varies according to the dorso-ventral location of the injection sites: the dorsal part of the Sp5O projects to the medial part of the VPM and the Po, and to the caudal part of the ZIv, as well as to the VPpc. The ventral part of the Sp5O projects to the lateral part of the VPM and the Po and to the rostral part of the ZIv. These results suggest that the trigemino-diencephalic pathways originating from the Sp5O are involved in the processing of gustatory and somatosensory information.
利用顺行示踪剂菜豆白细胞凝集素，在大鼠中研究了从三叉神经脊束核吻侧亚核（Sp5O）到间脑的传出投射组织。本研究证实了源自Sp5O的三叉丘脑通路的存在，并详细描述了它们的分布。Sp5O的主要间脑靶点是对侧的腹后内侧丘脑核（VPM）、丘脑后核（Po）和未定带腹侧部（ZIv），以及双侧的腹后丘脑核小细胞部（VPpc）。这些投射的分布根据注射部位的背腹位置而变化：Sp5O的背侧部分投射到VPM和Po的内侧部分、ZIv的尾部以及VPpc。Sp5O的腹侧部分投射到VPM和Po的外侧部分以及ZIv的嘴侧部分。这些结果表明，源自Sp5O的三叉间脑通路参与味觉和躯体感觉信息的处理。
