Bardenheier Barbara H, Yusuf Hussain R, Rosenthal Jorge, Santoli Jeanne M, Shefer Abigail M, Rickert Donna L, Chu Susan Y
Immunization Services Division, National Immunization Program, Centers for Disease Control and Prevention, 1600 Clifton Road, MS E-52, Atlanta, GA 30333, USA.
Public Health Rep. 2004 Sep-Oct;119(5):479-85. doi: 10.1016/j.phr.2004.07.005.
Risk factors for underimmunization at 3 months of age are not well described. This study examines coverage rates and factors associated with under-immunization at 3 months of age in four medically underserved areas.
During 1997-1998, cross-sectional household surveys using a two-stage cluster sample design were conducted in four federally designated Health Professional Shortage Areas. Respondents were parents or caregivers of children ages 12-35 months: 847 from northern Manhattan, 843 from Detroit, 771 from San Diego, and 1,091 from rural Colorado. A child was considered up-to-date (UTD) with vaccinations at 3 months of age if documentation of receipt of diphtheria-tetanus-pertussis, polio, haemophilus influenzae type B, and hepatitis B vaccines was obtained from a provider or a hand-held vaccination card, or both.
Household response rates ranged from 79% to 88% across sites. Vaccination coverage levels at 3 months of age varied across sites: 82.4% in northern Manhattan, 70.5% in Detroit, 82.3% in San Diego, and 75.8% in rural Colorado. Among children who were not UTD, the majority (65.7% to 71.5% per site) had missed vaccines due to missed opportunities. Factors associated with not being UTD varied by site and included having public or no insurance, >/=2 children living in the household, and the adult respondent being unmarried. At all sites, vaccination coverage among WIC enrollees was higher than coverage among children eligible for but not enrolled in WIC, but the association between UTD status and WIC enrollment was statistically significant for only one site and marginally significant for two other sites.
Missed opportunities were a significant barrier to vaccinations, even at this early age. Practice-based strategies to reduce missed opportunities and prenatal WIC enrollment should be focused especially toward those at highest risk of underimmunization.
3月龄时疫苗接种不足的风险因素尚未得到充分描述。本研究调查了四个医疗服务欠缺地区3月龄时的疫苗接种覆盖率及与疫苗接种不足相关的因素。
1997年至1998年期间,在四个联邦指定的卫生专业人员短缺地区采用两阶段整群抽样设计进行了横断面家庭调查。受访者为12至35月龄儿童的父母或照料者:来自曼哈顿北部的有847人,来自底特律的有843人,来自圣地亚哥的有771人,来自科罗拉多农村地区的有1091人。如果从医疗机构或手持疫苗接种卡或两者处获得了白喉-破伤风-百日咳、脊髓灰质炎、B型流感嗜血杆菌和乙肝疫苗接种记录,则该儿童被视为3月龄时疫苗接种及时。
各地区家庭应答率在79%至88%之间。3月龄时的疫苗接种覆盖率在各地区有所不同:曼哈顿北部为82.4%,底特律为70.5%,圣地亚哥为82.3%,科罗拉多农村地区为75.8%。在疫苗接种不及时的儿童中,大多数(每个地区为65.7%至71.5%)因错过接种机会而未接种疫苗。与疫苗接种不及时相关的因素因地区而异,包括拥有公共保险或无保险、家庭中居住有≥2名儿童以及成年受访者未婚。在所有地区,参加妇女、婴儿和儿童营养补充计划(WIC)的儿童的疫苗接种覆盖率高于符合WIC资格但未参加的儿童,但疫苗接种及时状况与WIC登记之间的关联仅在一个地区具有统计学意义,在另外两个地区具有边缘统计学意义。
即使在这么小的年龄,错过接种机会也是疫苗接种的一个重大障碍。基于实践的减少错过接种机会的策略以及产前WIC登记应特别针对疫苗接种不足风险最高的人群。