Abramson Jeff, Kaback H Ronald, Iwata So
Department of Biological Sciences, Imperial College London, London SW7 2AZ, UK.
Curr Opin Struct Biol. 2004 Aug;14(4):413-9. doi: 10.1016/j.sbi.2004.07.005.
Structural knowledge of the major facilitator superfamily has dramatically increased during the past year with the emergence of the structures of three members of this family of transporters. All three structures reveal 12 transmembrane helices forming two distinct domains, and could imply that members of this superfamily have preserved both secondary and tertiary structure elements during evolution.
在过去一年里，随着该转运蛋白家族三个成员结构的出现，主要易化子超家族的结构知识有了显著增加。所有这三种结构都显示有12个跨膜螺旋形成两个不同的结构域，这可能意味着该超家族成员在进化过程中保留了二级和三级结构元件。
