Kun Gao, Wan Mingxi
The Key Laboratory of Biomedical Information Engineering of Ministry of Education, Department of Biomedical Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, People's Republic of China.
Ultrasound Med Biol. 2004 Jul;30(7):991-8. doi: 10.1016/j.ultrasmedbio.2004.05.004.
The effects of fascia lata on high intensity focused ultrasound (US), or HIFU,-induced lesions were demonstrated through comparison with and without fascia lata in bovine thigh muscle tissue. Experiments were conducted in an arrangement with a three-way multiscan ultrasonic inspection system and imaging done by B-mode US. Bovine thigh muscle (8-cm thick) was treated with 1.5 MHz for 8 s. Spatial peak intensity (ISP) was 3000 W/cm2. B-mode US imaging detected appearance at the HIFU treatment site. At a free-field intensity of 4000 W/cm2, the observed lesion length (along the axis) with fascia lata was 12 +/- 1.82 mm, compared with 4 +/- 1.54 mm for samples without fascia lata. At 3000 W/cm2, the values for samples with fascia lata and samples without fascia lata, respectively, were 13 +/- 1.50 mm and 2 +/- 1.42 mm. During a 30-s exposure, at ISP of 2000 W/cm2, the peak temperature reached 41 degrees C in samples without fascia lata and 70 degrees C in samples with fascia lata. At ISP of 3000 and 4000 W/cm2, the peak temperature reached, respectively, 73 degrees C and 84 degrees C in samples without fascia lata, compared with 102 degrees C and 104 degrees C, respectively, for samples with fascia lata. The results confirm that fascia lata contributes to increasing tissue necrosis, temperature elevation and echogenicity in US images.
通过在牛大腿肌肉组织中对比有无阔筋膜的情况，证明了阔筋膜对高强度聚焦超声（HIFU）所致损伤的影响。实验采用三路多扫描超声检查系统进行，并通过B型超声成像。用1.5MHz的频率对8厘米厚的牛大腿肌肉进行8秒的治疗。空间峰值强度（ISP）为3000W/cm²。B型超声成像检测到HIFU治疗部位的情况。在自由场强度为4000W/cm²时，有阔筋膜的样本观察到的损伤长度（沿轴）为12±1.82毫米，而没有阔筋膜的样本为4±1.54毫米。在3000W/cm²时，有阔筋膜和没有阔筋膜的样本的值分别为13±1.50毫米和2±1.42毫米。在2000W/cm²的ISP下进行30秒的暴露时，没有阔筋膜的样本峰值温度达到41℃，有阔筋膜的样本达到70℃。在3000W/cm²和4000W/cm²的ISP下，没有阔筋膜的样本峰值温度分别达到73℃和84℃，而有阔筋膜的样本分别为102℃和104℃。结果证实，阔筋膜有助于增加组织坏死、温度升高以及超声图像中的回声性。
