在德黑兰成年男性中，腰臀比是比其他人体测量指标更好的心血管危险因素筛查指标。
Waist-to-hip ratio is a better screening measure for cardiovascular risk factors than other anthropometric indicators in Tehranian adult men.
作者信息
Esmaillzadeh A, Mirmiran P, Azizi F
机构信息
Endocrine Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran.
出版信息
Int J Obes Relat Metab Disord. 2004 Oct;28(10):1325-32. doi: 10.1038/sj.ijo.0802757.
BACKGROUND
It is essential to identify the best anthropometric index in any population to predict chronic disease risk.
OBJECTIVE
To compare the ability of waist circumference (WC), body mass index (BMI), waist-to-hip ratio (WHpR) and waist-to-height ratio (WHtR) to predict cardiovascular risk factors in an urban adult population of Tehranian men.
DESIGN
Population-based cross-sectional study.
SUBJECTS
A representative sample of 4,449 men aged 18-74 y, participants of the Tehran Lipid and Glucose Study
METHODS
Demographic data were collected; anthropometric indices and blood pressure were measured according to standard protocol. In the 18-34 y age category, cutoff points for BMI, WHpR, WHtR and WC were 24 kg/m(2), 0.86, 0.47 and 81 cm, respectively. In the 35-54 y age category these cut points were 26 kg/m(2), 0.91, 0.52 and 89 cm, and in the 55-74 y age category 26 kg/m(2), 0.95, 0.54 and 91 cm, respectively. Hypertension was defined based on JNC VI. Biochemical analysis was conducted on fasting blood samples. Diabetes was defined as fasting plasma glucose > or =126 mg/dl or 2hPG > or =200 mg/dl and dyslipidemia based on ATP III. The presence of 'at least one risk factor' from the three major cardiovascular risk factors (hypertension, dyslipidemia and diabetes) was also evaluated.
RESULTS
Mean age of men was 41.8+/-15.4 y. Mean BMI, WHpR, WC and WHtR for subjects were 25.6+/-4.2 kg/m(2), 0.91+/-0.07, 87.7+/-11.7 cm and 0.51+/-0.02, respectively. Dyslipidemia and 'at least one risk factor' are more prevalent risk categories. Although all anthropometric indicators had a significant association to cardiovascular risk factors, WHpR had the highest correlation coefficients compared to other anthropometric measures. For all risk factors in all age categories, the highest odds ratios were pertained to WHpR. Of the four individual indicators, WHpR had the highest sensitivity, specificity and accuracy to predict cardiovascular risk factors. Cutoff points for WHpR were seen to have a higher percentage of correct prediction than BMI, WC and WHtR in all age categories.
CONCLUSION
It is concluded that WHpR is a better predictor for cardiovascular risk factors than BMI, WC and WHtR in Tehranian adult men.
背景
确定任何人群中预测慢性病风险的最佳人体测量指标至关重要。
目的
比较腰围（WC）、体重指数（BMI）、腰臀比（WHpR）和腰高比（WHtR）预测德黑兰成年男性城市人群心血管危险因素的能力。
设计
基于人群的横断面研究。
对象
德黑兰血脂与血糖研究的4449名年龄在18 - 74岁男性的代表性样本。
方法
收集人口统计学数据；按照标准方案测量人体测量指标和血压。在18 - 34岁年龄组中，BMI、WHpR、WHtR和WC的切点分别为24kg/m²、0.86、0.47和81cm。在35 - 54岁年龄组中，这些切点分别为26kg/m²、0.91、0.52和89cm，在55 - 74岁年龄组中分别为26kg/m²、0.95、0.54和91cm。高血压根据美国国家高血压教育计划第六次报告（JNC VI）定义。对空腹血样进行生化分析。糖尿病定义为空腹血糖≥126mg/dl或餐后2小时血糖≥200mg/dl，血脂异常根据成人治疗小组第三次报告（ATP III）定义。还评估了三大心血管危险因素（高血压、血脂异常和糖尿病）中“至少一种危险因素”的存在情况。
结果
男性的平均年龄为41.8±15.4岁。受试者的平均BMI、WHpR、WC和WHtR分别为25.6±4.2kg/m²、0.91±0.07、87.7±11.7cm和0.51±0.02。血脂异常和“至少一种危险因素”是更普遍的风险类别。尽管所有人体测量指标与心血管危险因素均有显著关联，但与其他人体测量指标相比，WHpR的相关系数最高。对于所有年龄组的所有危险因素，最高比值比均与WHpR相关。在四个单独指标中，WHpR预测心血管危险因素的敏感性、特异性和准确性最高。在所有年龄组中，WHpR的切点比BMI、WC和WHtR具有更高的正确预测百分比。
结论
得出结论，在德黑兰成年男性中，WHpR比BMI、WC和WHtR更能预测心血管危险因素。
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