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[全氟碳化合物所致急性心肌梗死时心脏血流动力学及冠状动脉血流的变化]

[Changes in the cardiac hemodynamics and coronary blood flow in acute myocardial infarction due to perftoran].

作者信息

Aliev O M

出版信息

Anesteziol Reanimatol. 2004 May-Jun(3):62-3.

PMID:15314866
Abstract

One hundred and twenty patients with acute myocardium infarction, who were receiving perftoran, were analyzed within the case study. The microcirculation condition was determined by biomicroscopy of the eye conjunctiva capillaries. Changes in capillaries were evaluated by the Ditzel classification. Hemostasis was evaluated by coalugram. The condition of the myocardium was examined by electrocardiography and Echo-cardiography. The contractive ability of the myocardium was assessed by a shortening degree of the anterior-posterior size and by the ejection fraction. According to the study results, the administration of perftoran increased the number of functioning capillaries, decreased the venous congestion and reduced the diameter of arterioles and venules. Hypercoagulation was significantly decreasing. The general evaluation of the contractive ability of myocardium was satisfactory in all patients.

摘要

在该病例研究中,对120名正在接受perftoran治疗的急性心肌梗死患者进行了分析。通过眼结膜毛细血管的生物显微镜检查来确定微循环状况。根据迪策尔分类法评估毛细血管的变化。通过凝血图评估止血情况。通过心电图和超声心动图检查心肌状况。通过前后径缩短程度和射血分数评估心肌的收缩能力。根据研究结果,使用perftoran可增加功能正常的毛细血管数量,减少静脉淤血,并减小小动脉和小静脉的直径。高凝状态明显减轻。所有患者心肌收缩能力的总体评估结果令人满意。

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