Rymarz Ewa, Mosiewicz Jerzy, Hanzlik Janusz
Department of Internal Medicine, Medical University of Lublin, Lublin, Poland.
Ann Univ Mariae Curie Sklodowska Med. 2003;58(1):5-10.
For the estimation of the role of GIK in diminishing post-infarction necrosis, the influence of GIK mixture on indicative enzymes (such as: CPK, CK-MB, ASPAT and ALAT) was checked. In a group of patients treated with GIK the increase of CPK and CK-MB activity after 24 hours was less pronounced, comparing to placebo group and differences between groups were at the borderline of statistical significance. Other parameters in both groups did not change in statistically significant way. A noted profitable change in CPK and CK-MB activity speaks in favour of GIK mixture and it is role in diminishing myocardial necrosis.
为评估极化液（GIK）在减少心肌梗死后坏死方面的作用，检测了GIK混合物对指示酶（如：肌酸磷酸激酶（CPK）、肌酸激酶同工酶（CK-MB）、天冬氨酸氨基转移酶（ASPAT）和丙氨酸氨基转移酶（ALAT））的影响。与安慰剂组相比，接受GIK治疗的患者组在24小时后CPK和CK-MB活性的增加不太明显，两组之间的差异处于统计学意义的临界值。两组中的其他参数没有统计学意义上的显著变化。CPK和CK-MB活性的明显有益变化表明GIK混合物有益，且其在减少心肌坏死方面发挥作用。
