慢性丙型肝炎男性患者血清中硫酸脱氢表雄酮和雄烯二酮的浓度

Dehydroepiandrosterone sulphate and androstenedione concentration in the serum of male patients with chronic hepatitis C.

作者信息

Fota-Markowska Hanna, Kiciak Sławomir, Modrzewska Roma, Krzowska-Firych Joanna, Borowicz Irena

机构信息

Department of Infectious Diseases, Medical University of Lublin.

出版信息

Ann Univ Mariae Curie Sklodowska Med. 2003;58(1):297-301.

PMID:15315002

Abstract

In this study the dynamics of DHEAS and androstenedione serum concentration in male patients with CHC infection were analyzed. The study group consisted of 52 men, 26 of them being the control group of healthy men. The DHEAS and androstenedione serum concentration was determined twice with radioimmunological method (RIA). 1. Mean values of suprarenal androgens serum concentration in male patients with CHC infection were lower than in healthy men and the observed differences were incidental, 2. There was no correlation between dehydroepiandrosterone and androstenedione serum concentration in male patients with CHC infection.

摘要

本研究分析了慢性丙型肝炎（CHC）感染男性患者血清硫酸脱氢表雄酮（DHEAS）和雄烯二酮浓度的动态变化。研究组由52名男性组成，其中26名为健康男性对照组。采用放射免疫分析法（RIA）测定血清DHEAS和雄烯二酮浓度两次。1. CHC感染男性患者血清肾上腺雄激素浓度平均值低于健康男性，且观察到的差异为偶然现象；2. CHC感染男性患者血清脱氢表雄酮和雄烯二酮浓度之间无相关性。