Madarame H, Itoh A, Hirose M, Ogihara K
Veterinary Teaching Hospital, School of Veterinary Medicine, Azabu University, Sagamihara-shi, Kanagawa-ken 229-8501, Japan.
J Vet Med A Physiol Pathol Clin Med. 2004 Jun;51(5):232-6. doi: 10.1111/j.1439-0442.2004.00635.x.
Spontaneous subcutaneous extraskeletal osteosarcoma was diagnosed in the subcutaneous tissue of two Djungarian hamsters. Histologically, the tumour was characterized by multiple nests of osseous and cartilaginous components within a proliferation of pleomorphic cells. No abnormality was observed in any skeletal bones and no change suggesting tumorous growth was observed in any other sites. This is the first report of extraskeletal osteosarcomas in Djungarian hamsters.
在两只西伯利亚仓鼠的皮下组织中诊断出自发性皮下骨外骨肉瘤。组织学上，肿瘤的特征是在多形性细胞增殖内有多个骨和软骨成分的巢。在任何骨骼中均未观察到异常，在任何其他部位也未观察到提示肿瘤生长的变化。这是关于西伯利亚仓鼠骨外骨肉瘤的首次报告。
