Langenbach A, Anderson M A, Dambach D M, Sorenmo K U, Shofer F D
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6010, USA.
J Am Anim Hosp Assoc. 1998 Mar-Apr;34(2):113-20. doi: 10.5326/15473317-34-2-113.
Extraskeletal osteosarcomas (EOSs) are rare tumors that arise in various soft-tissue sites (e.g., gastrointestinal tract, subcutaneous tissue, spleen, liver, skin, kidney, urinary bladder, muscle, thyroid gland, eye, and mammary glands). Soft-tissue osteosarcomas (STOs) occur in older dogs with no sex predilection; beagles and rottweilers are at higher risk. Mammary gland osteosarcomas (MGOs) occur in older females; mixed-breed dogs, German shepherd dogs, and miniature poodles are at higher risk. The median survival time for cases with STO was 26 days, and the major cause of death was local recurrence (92%). The median survival time for cases with MGO was 90 days, and the major cause of death was pulmonary metastasis (62.5%).
骨外骨肉瘤（EOSs）是一种罕见的肿瘤，发生于各种软组织部位（如胃肠道、皮下组织、脾脏、肝脏、皮肤、肾脏、膀胱、肌肉、甲状腺、眼睛和乳腺）。软组织骨肉瘤（STOs）发生于年龄较大的犬类，无性别倾向；比格犬和罗威纳犬的风险更高。乳腺骨肉瘤（MGOs）发生于年龄较大的雌性犬；混血犬、德国牧羊犬和迷你贵宾犬的风险更高。STO病例的中位生存时间为26天，主要死亡原因是局部复发（92%）。MGO病例的中位生存时间为90天，主要死亡原因是肺转移（62.5%）。
