Lake A M, Scott D W, Miller W H, Erb H N
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA.
J Vet Med A Physiol Pathol Clin Med. 2004 Jun;51(5):249-53. doi: 10.1111/j.1439-0442.2004.00629.x.
A study was conducted to characterize the gross and cytological characteristics of secretions from normal canine anal sacs. Fifty dogs with no recent history of anal-sac disease were selected consecutively and their anal sacs manually expressed. Of the 47 dogs with known or estimated ages, 27 were < 1 year olds. However, these youngest dogs were not significantly different from the rest in cell counts, viscosity, or presence of dark or light solid portions of the secretions. For all dogs combined, the secretions typically contained 41 (median) corneocytes per 400x magnification microscopic field, lots of basophilic background debris, and a mixture of Gram-positive cocci (173 per field; median), Gram-positive rods (29 per field; median), and Gram-negative rods (two per field; median). Although median counts across 10 400x fields per sac indicated no leucocytes or yeasts, many of the normal dogs had an occasional 400x field with non-degenerate neutrophils and yeasts. Erythrocytes were not a feature of these anal-sac secretions, and mononuclear leucocytes were found only rarely. Extreme heterogeneity existed in gross colour, consistency and the amount of solid material. Thus, these latter parameters probably would not be valid indicators of anal-sac disease.
进行了一项研究，以描述正常犬肛门囊分泌物的大体和细胞学特征。连续挑选了50只近期无肛门囊疾病史的犬，并手动挤压它们的肛门囊。在47只已知或估计年龄的犬中，27只为1岁以下。然而，这些最年幼的犬在细胞计数、粘度或分泌物深色或浅色固体部分的存在方面与其他犬没有显著差异。对于所有犬的分泌物综合来看，在400倍放大倍数的显微镜视野下，分泌物通常每视野含有41个（中位数）角质形成细胞、大量嗜碱性背景碎屑，以及革兰氏阳性球菌（每视野173个；中位数）、革兰氏阳性杆菌（每视野29个；中位数）和革兰氏阴性杆菌（每视野2个；中位数）的混合物。尽管每个囊10个400倍视野的中位数计数显示没有白细胞或酵母，但许多正常犬偶尔会有一个400倍视野含有未退化的中性粒细胞和酵母。红细胞不是这些肛门囊分泌物的特征，单核白细胞也很少发现。分泌物的大体颜色、稠度和固体物质的量存在极大的异质性。因此，这些后述参数可能不是肛门囊疾病的有效指标。
