Adriaanse M C, Snoek F J, Dekker J M, Spijkerman A M W, Nijpels G, Twisk J W R, van der Ploeg H M, Heine R J
Institute for Research in Extramural Medicine (EMGO-Institute), VU University Medical Center, Amsterdam, the Netherlands.
Diabet Med. 2004 Sep;21(9):992-8. doi: 10.1111/j.1464-5491.2004.01276.x.
To examine the impact of the diagnosis of Type 2 diabetes on psychological well-being and perceived health status in subjects who participated in a targeted population-screening programme.
This study was conducted within the framework of a screening project in the general (aged 50-75 years) Dutch population. The final study population consisted of 259 subjects with a high-risk score on the Symptom Risk Questionnaire; 116 of whom were subsequently detected with Type 2 diabetes and 143 who were non-diabetic. The impact was assessed approximately 2 weeks (shortly) and 6 and 12 months after the diagnosis, using the 12-item Well-Being Questionnaire (W-BQ12) and the Medical Outcomes Study Short Form 36 (SF-36), respectively. Analyses of co-variance (ancova) were used.
Approximately 2 weeks after the diagnosis, no significant mean differences were found on either the W-BQ12 or the SF-36, between the screening-detected Type 2 diabetes subjects and the non-diabetic subjects. Six months after the diagnosis, we found lower scores in the screening-detected Type 2 diabetes subjects compared with the non-diabetic subjects on the SF-36 dimensions Role Physical (mean difference (95% CI); -8.2 (-16.2; -0.1); P = 0.046) and Role Emotional (mean difference (95% CI); -7.9 (-15.3; -0.5); P = 0.038). One year after the test results, no significant mean differences were found between both groups on either instrument (W-BQ12; SF-36).
The diagnosis of Type 2 diabetes has no substantial adverse or positive effect on psychological well-being and perceived health status, shortly, and 6 and 12 months after the diagnosis.
研究2型糖尿病诊断对参与目标人群筛查项目的受试者心理健康和自我感知健康状况的影响。
本研究在荷兰普通人群（年龄50 - 75岁）筛查项目框架内进行。最终研究人群包括259名在症状风险问卷上得分较高的受试者；其中116人随后被诊断为2型糖尿病，143人未患糖尿病。分别在诊断后约2周（短期）、6个月和12个月，使用12项幸福感问卷（W - BQ12）和医学结局研究简表36（SF - 36）评估影响。采用协方差分析（ancova）。
诊断后约2周，筛查发现的2型糖尿病受试者与非糖尿病受试者在W - BQ12或SF - 36上均未发现显著的平均差异。诊断后6个月，我们发现筛查发现的2型糖尿病受试者在SF - 36的角色 - 生理维度（平均差异（95%可信区间）；-8.2（-16.2；-0.1）；P = 0.046）和角色 - 情感维度（平均差异（95%可信区间）；-7.9（-15.3；-0.5）；P = 0.038）上得分低于非糖尿病受试者。测试结果1年后，两组在任何一种量表（W - BQ12；SF - 36）上均未发现显著的平均差异。
2型糖尿病诊断在诊断后不久、6个月和12个月时，对心理健康和自我感知健康状况没有实质性的不良或积极影响。
